TREATING C3 GLOMERULOPATHY WITH ECULIZUMAB

Treating C3 glomerulopathy with eculizumab

Abstract Background C3 glomerulopathy (C3G) is a rare, but severe glomerular disease with grim prognosis.The complex pathogenesis is just unfolding, and involves acquired as well as inherited dysregulation of the alternative pathway of the complement cascade.Currently, there is no established therapy.Treatment with the C5 complement inhibitor eculi

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